have you tried the door handle? i know that my remote has never opened the door by itself.... i have to use the handle.
no seriously, you need to give a little more info than "it wont open"...
are you unable to open from outside and inside?
does the inside lock show that the door is supposed to be unlocked?
is the child safety switch engaged?
have you tried using the power door lock switch on the drivers door to unlock the doors?
it's extremely hard to diagnose a problem over the internet without any information.
~mike