For a good 2-3 years now, while driving on the highway hitting the wind at some magical angle, the top of my door would get pushed out a fraction and let a tiny amount of wind through. This creates a very loud and annoying whistling noise. In the past, I would simply reach up with my left hand while driving and squeeze the door and the frame together to stop the noise. First thing I did when I originally encountered this was to readjust the door so that it would close as far toward the inside of the vehicle as I could get it. I even broke down and put in some thick weatherstripping this past summer thinking that may help, but it didn't. After more thought, it was obvious to me that overall exterior sounds were much louder than when new. I stopped by the dealer last Friday because my damned TPMS light was on again (5th time in 2011, although it would have been more but I would drive for months at a time before getting it reset). I picked up a few parts and also broke down and bought a new door seal for ~$60. As soon as I pulled the new one out of the box and put it next to the original, I could see why I was having the problem.
I doubt anyone else has encountered this, or at least nobody else has posted about it, but I'm just writing this as an FYI to replace the door seal if you have the same problem.
Here's the new seal installed:
Here is the old seal compared to the new. You can see how flattened the old one is:
